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Left atrial enlargement
Left atrial enlargement (LAE) or left atrial dilation refers to enlargement of the left atrium (LA) of the heart, and is a form of cardiomegaly.
== Causes ==
In the general population, obesity appears to be the most important risk factor for LAE. LAE has been found to be correlated to body size, independent of obesity, meaning that LAE is more common in people with a naturally large body size. 〔 〕 Also, a study found that LAE can occur as a consequence of atrial fibrillation (AF), although another study found that AF by itself does not cause LAE. The latter study also showed that the persistent type of AF was associated with LAE, but the number of years that a subject had AF was not.〔 See p. 2560 Left ventricular filling pressure, LAV, and AF.〕
Obstructive sleep apnea (OSA) may be a cause of LAE in some cases. When an OSA event occurs, there is an attempt to breathe with an obstructed airway and the pressure inside the chest is suddenly lowered. The negative intrathoracic pressure may cause the left atrium to expand and stretch its walls during each OSA event. Over time, the repetitive stretching of the left atrium may result in a persistent left atrial enlargement.〔 See section 5.1.〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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